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Embryology: Limb Development

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Product Type: viz-Documents (docs, outlines, guides, handbooks)
Product Audience: College Undergraduate,College Postgraduate
Length: Short (< 20 pages)
Language: English
License: CC BY (You can use, share, and adapt the content - even for commercial use - as long as you give proper credit to the creator.)
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Table Of Contents

Embryology: Limb Development

I. Introduction
A. Importance of limb development in embryology
B. Overview of limb bud formation and patterning

II. Limb Bud Formation and Growth
A. Initiation of limb buds
B. Outgrowth and elongation of limb buds
C. Role of apical ectodermal ridge (AER) and zone of polarizing activity (ZPA)

III. Limb Patterning
A. Establishment of proximal-distal and anterior-posterior axes
B. Sonic hedgehog (Shh) signaling and limb patterning

IV. Tissue Differentiation
A. Differentiation of mesenchyme into skeletal elements (cartilage and bone)
B. Differentiation of muscle, connective tissue, blood vessels, and nerves

V. Limb Rotation and Positioning
A. Rotation and final positioning of limbs
B. Extrinsic factors influencing limb positioning

VI. Vascularization and Innervation
A. Development of blood vessels in limbs
B. Innervation of limb muscles and sensory structures

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